Glutein sensitive enteropathy(coeliac disease)
An immunologic ally mediated intolerance to Glutein containing
grains(wheat,rye,barley and possibly oat) result in small intestinal villous atrophy.
Usually begins between 6-18 months and include apathy,irritability,pain,vomiting, chronic diarrhea, failure to thrive,steatorrhea,abdominal distention, wasted skeletal muscle mass, clubbing of finger and peripheral edema also may occur. Malabsorption occurs especially of vitamin D ,Folic acid ,Iron and Calcium.
2 -Clinical examination.
3- Jeujenal biopsy shows subtotal villous atrophy, and then 2nd specimen show improvement with Glutein free diet.
consist of permanent elimination of Glutein containing food.